A Simple and Highly Sensitive Thymine Sensor for Mercury Ion Detection Based on Surface Enhanced Raman Spectroscopy and the Mechanism Study
نویسندگان
چکیده
Mercury ion (Hg2+) is recognized as one of the most toxic metal ions for the environment and for human health. Techniques utilized in the detection of Hg2+ are an important factor. Herein, a simple thymine was successfully employed as the surface enhanced Raman spectroscopy sensor for Hg2+ ion detection. The limit of detection (LOD) of the developed sensor is better than 0.1 nM (0.02 ppb). This sensor can also selectively distinguish Hg2+ ions over 7 types of alkali, heavy metal and transition-metal ions. Moreover, the LOD of the sensor can even achieve 1 ppb in practical application in the nature system, which is half the maximum allowable level (10 nM, 2 ppb) stipulated in the US Environmental Protection Agency standard. Further investigation of the thymine-Hg2+-thymine coordination mechanism provides a possible means of detecting other metal ions by replacing the metal ion-specific ligands. This work paves the way for the detection of toxic metal ions and environmental problems.
منابع مشابه
Biosensing Based on Surface-Enhanced Raman Spectroscopy by Using Metal Nanoparticles
Surface-enhanced Raman spectroscopy (SERS) is a promising tool in the analytical science because it provides good selectivity and sensitivity without the labeling process required by fluorescence detection. This technique consists of locating the target analyte on nanometer range of roughed Au-nanoparticles. The presence of the metal nanoparticles provides a tremendous enhancement to the result...
متن کاملIntelligent and ultrasensitive analysis of mercury trace contaminants via plasmonic metamaterial-based surface-enhanced Raman spectroscopy.
Label-free molecular logic gates (AND, INHIBIT, and OR) are constructed based on specific conformation modulation of a guanine- and thymine-rich DNA, while the optical readout is enabled by the tunable metamaterials which serve as a substrate for surface enhanced Raman spectroscopy. The DNA logic is simple to operate, highly reproducible, and can be stimulated by ultra-low concentration of the ...
متن کاملFabrication of an Electrochemical Sensor Based on a New Nano-ion Imprinted Polymer for Highly Selective and Sensitive Determination of Molybdate
In this work a new chemically modified carbon paste electrode was constructed for accurate, simple, sensitive and selective determination of molybdenum (VI) ions. The results of modified electrode by an ion imprinted polymer were compared with those obtained with carbon paste electrode. The results showed the stripping peak currents had a dramatic increase at the modified electrode. Under the o...
متن کاملGlass Nanopillar Array Based Nanoplasmonic Lab-on-a-chip for Highly Sensitive Surface Enhanced Raman Spectroscopy
ABSTRACT This work presents the novel glass nanopillar array based nanoplasmonic lab-on-a-chip for highly sensitive surface-enhanced Raman Spectroscopy (SERS). In this work, large-area glass nanopillar arrays are fabricated on both sides of the wafers by combination of metal dewetting and reactive-ion-etching (RIE) process. Metal layer is deposited onto one side to construct nanoplasmonic biose...
متن کاملMolecular Diagnosis of Plasma Phenylalanine in Neonates with Phenylketonuria Disease Using Biological Sensors Based on Surface-Enhanced Raman Spectroscopy (SERS)
In this study, silver nanoparticles were chemically synthesized and deposited on glass substrates using a reducing agent of sucrose, at 50°C. Different characterizations including atomic force microscopy (AFM), field emission scanning electron microscopy (FESEM), and Raman spectroscopy were obtained to study silvery substrates. Then, the silvery substrates were used as the SERS substrates to de...
متن کامل